文献类型：期刊文献

英文题名：Adamantane-1-Carbonyl-Directed C-H Borylation and Hydroxylation of Benzenethiols

作者：Xu, Xiaobo[1,2];Wu, Gaorong[1,2];Yang, Zhaoziyuan[1,2];Liu, Xian[1,2];Hao, Liqiang[1,2];Wang, Yangyang[1,2];Ma, Zhihong[3];Ji, Yafei[1,2]

机构：[1]East China Univ Sci & Technol, Engn Res Ctr Pharmaceut Proc Chem, Minist Educ, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China;[3]Biotalk Co LTD, Shanghai 200092, Peoples R China

年份：2022

卷号：24

期号：39

起止页码：7163

外文期刊名：ORGANIC LETTERS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000862795100001)，CCR-EXPANDED(收录号:WOS:000862795100001)】；

基金：ACKNOWLEDGMENTS We gratefully thank the National Natural Science Foundation of China (Project No. 21676088) for financial support.

语种：英文

摘要：A novel route has been described for C-H borylation and hydroxylation of benzenethiols directed by adamantane-1carbonyl using BBr3. The protocol generates corresponding arylboronic esters and phenols in moderate to excellent yields under metal-free conditions. In addition, the borylated product can be transformed and the directing group can be removed in good yields, which will facilitate the synthesis of structurally diverse benzenethiols.