文献类型：期刊文献

英文题名：Synthesis of the scalarane sesterterpenoid 16-deacetoxy-12-epi- scalarafuranacetate

作者：Chen, Xi-Bo[1]; Yuan, Qian-Jia[1]; Wang, Jing[1]; Hua, Si-Kai[1]; Ren, Jiangmeng[1]; Zeng, Bu-Bing[1]

机构：[1] School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China

年份：2011

卷号：76

期号：17

起止页码：7216

外文期刊名：Journal of Organic Chemistry

收录：EI(收录号：20113514290346)

语种：英文

摘要：The marine natural product 16-deacetoxy-12-epi-scalarafuranacetate, isolated from Spongua officinalis, was synthesized in 18 linear steps, starting from (-)-sclareol, with high stereoselectivity and an overall yield of 6.1%. The intermediate 16-deacetoxy-12-epi-scalarafuran could be easily transformed into a series of natural scalarane sesterterpenoids in a few steps. ? 2011 American Chemical Society.