文献类型：期刊文献

英文题名：An Axially Chiral Quinoline-2-Carboxylic Acid-Cu Catalyst for Enantioselective Synthesis of C 2- and C 1-Symmetric BINOLs

作者：Shen, Ahui[1];Xu, Jun[2];Gao, Jun[2];Cen, Shouyi[2];Zhang, Zhipeng[1]

机构：[1]East China Univ Sci & Technol, Feringa Nobel Prize Scientist Joint Res Ctr, Frontiers Sci Ctr Materiobiol & Dynam Chem, Sch Chem & Mol Engn,Key Lab Adv Mat & Joint Int Re, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Sch Chem & Mol Engn, Shanghai 200237, Peoples R China

年份：2024

卷号：89

期号：17

起止页码：12842

外文期刊名：JOURNAL OF ORGANIC CHEMISTRY

收录：;EI(收录号：20243416900432);WOS:【SCI-EXPANDED(收录号:WOS:001289859700001)，CCR-EXPANDED(收录号:WOS:001289859700001)】；

基金：We thank the Research Center of Analysis and Test, East China University of Science and Technology, for help with the characterization. We acknowledge the National Natural Science Foundation of China (22371072, 21702059), Fundamental Research Funds for the Central Universities (222201717003, JKVJ1241010, YJ0142225, SLJ13233303), Shanghai Municipal Science and Technology Major Project (2018SHZDZX03), Program of Introducing Talents of Discipline to Universities (B16017), and the "Thousand Plan" Youth Program for financial support.

语种：英文

外文关键词：Chitosan - Coordination reactions - Synthesis (chemical)

摘要：The in situ dimeric coordination of two chiral ligands bearing quinoline-2-carboxylic acid units and substituted BINOL backbones with a copper ion generates a new chiral catalyst for oxidative homo- and cross-coupling of various 2-naphthols, enabling enantioselective synthesis of a broad range of highly useful diversely substituted C- 2- and C- 1-symmetric BINOLs in up to 96% yield with good to excellent enantioselectivities (up to 98:2 e.r.).