文献类型：期刊文献

英文题名：Palladium-catalyzed double coupling reaction of terminal alkynes with isocyanides: a direct approach to symmetricalN-aryl dialkynylimines

作者：Xi, Zhi-Wei[1];He, Yan[2,3];Liu, Li-Qiu[1];Wang, Ying-Chun[1]

机构：[1]Jishou Univ, Natl Demonstrat Ctr Expt Chem Educ, Hunan Engn Lab Analyse & Drugs Dev Ethnomed Wulin, Jishou 416000, Peoples R China;[2]East China Univ Sci & Technol, State Key Lab Chem Engn, Key Lab Adv Mat, Shanghai Key Lab Funct Mat Chem, 130 Meilong Rd, Shanghai 200237, Peoples R China;[3]East China Univ Technol, East China Univ Sci & Technol, 130 Meilong Rd, Shanghai 200237, Peoples R China

年份：2020

卷号：18

期号：40

起止页码：8089

外文期刊名：ORGANIC & BIOMOLECULAR CHEMISTRY

收录：;EI(收录号：20204409441164);WOS:【SCI-EXPANDED(收录号:WOS:000580494600008)，CCR-EXPANDED(收录号:WOS:000580494600008)】；

基金：We thank the National Natural Science Foundation of China (21762017) and the Hunan Province Natural Science Foundation of China (2020JJ4499).

语种：英文

外文关键词：Cyanides - Palladium

摘要：A novel and efficient one-pot synthesis of symmetricalN-aryl dialkynyliminesviapalladium-catalyzed and copper-promoted isocyanide insertion, cross-coupling and elimination has been developed. This method features readily available starting materials, mild reaction conditions and high atom efficiency as well as simple one-pot operation, which make this strategy highly attractive. Moreover, 2-iodobenzo[f]quinoline derivatives can be obtainedviaelectrophilic cyclization ofN-aryl dialkynylimines.