文献类型：期刊文献

英文题名：A new quantitative evaluation method of spiral drawing for patients with Parkinson's disease based on a polar coordinate system with varying origin

作者：Wang, Min[1];Wang, Bei[1];Zou, Junzhong[1];Nakamura, Masatoshi[2]

机构：[1]ECUST, Sch Informat Sci & Engn, Dept Automat, Shanghai 200237, Peoples R China;[2]Saga Univ, Res Inst Syst Control, Inst Adv Res & Educ, Saga 8400047, Japan

年份：2012

卷号：391

期号：18

起止页码：4377

外文期刊名：PHYSICA A-STATISTICAL MECHANICS AND ITS APPLICATIONS

收录：;EI(收录号：20122415107787);WOS:【SCI-EXPANDED(收录号:WOS:000306254700011)】；

语种：英文

外文关键词：Patients with Parkinson's disease; Hand movement in spiral drawing experiment; Polar coordinate system with varying origin; Deep brain stimulation; Feature extraction; Quantitative evaluation

摘要：Parkinson's disease (PD) is a common disease of the central nervous system among the elderly, and its complex symptoms bring up challenges for the clinical diagnosis. In this paper, a new method based on a polar coordinate system with varying origin was proposed in order to quantitatively evaluate the performance in spiral drawing tasks for patients with Parkinson's disease, since this method can assess the movement ability of spiral drawing before and after deep brain stimulation (DBS) among the patients. In this paper, three normal subjects and twelve PD patients participated in spiral drawing experiment. The hand movements of patients, before and after DBS, were recorded by a digitized tablet respectively in this experiment. And the variation of origin, radius, degree and other characteristics of hand movements were evaluated by introducing a set of parameters for feature extraction. The result showed that the proposed polar coordinate system embraced good performance in the quantitative evaluation of spiral drawing. Therefore, the proposed method overcame the limitation of data processes with fixed origin for diagnosis and evaluation, and by combining with extraction and analysis of characteristic parameters it had clinical significance in measuring the effectiveness of operation or treatment for the PD patients. (c) 2012 Elsevier B.V. All rights reserved.