文献类型：期刊文献

英文题名：Divalent and Oxabridged Neonicotinoids Constructed by Dialdehydes and Nitromethylene Analogues of Imidacloprid: Design, Synthesis, Crystal Structure, and Insecticidal Activities

作者：Shao, Xusheng[1];Fu, Hua[3];Xu, Xiaoyong[1];Xu, Xinglei[1];Liu, Zewen[2];Li, Zhong[1];Qian, Xuhong[1]

机构：[1]E China Univ Sci & Technol, Shanghai Key Lab Chem Biol, Sch Pharm, Shanghai 200237, Peoples R China;[2]Nanjing Agr Univ, Key Lab Monitoring & Management Plant Dis & Insec, Minist Agr, Nanjing 210095, Peoples R China;[3]Qinghai Univ, Chem Engn Coll, Dept Appl Chem, Xining 810016, Peoples R China

年份：2010

卷号：58

期号：5

起止页码：2696

外文期刊名：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000275087600013)】；

基金：This work was financially supported by the National Basic Research Program of China (973 Program, 2010CB126100), the National High Technology Research and Development Program of China (863 Program, 2006AA10A201), the National Science Foundation China Program Grant (20872034), and the Program for New Century Excellent Talents in University (NCET070284). This work was also partly supported by the Shanghai Foundation of Science and Technology (08391911600, OXD1401300, 073919107), the grant "Application of Nuclear Techniques in Agriculture" from the Chinese Minisiry of Agriculture (Grant 200803034), and the Shanghai Leading Academic Discipline Project, Project B507.111 Project 1307023.

语种：英文

外文关键词：Neonicotinoids; dialdehydes; imidacloprid; insecticide; oxabridge

摘要：A series of divalent and oxabridged neonicotinoids were synthesized by reactions of nitromethylene analogues of imidacloprid and dialdehydes, and their structures were confirmed by H-1 NMR, C-13 NMR, high-resolution mass spectroscopy, and X-ray diffraction analysis. The bioassays indicated that some of them were endowed with excellent insecticidal activities against cowpea aphid (Aphis craccivora), armyworm (Pseudaletia separata Walker), and brown planthopper (Nilaparvata lugens). Divalent neonicotinoid 6 and oxabridged 8a had higher activities than imidacloprid against cowpea aphids and armyworm; furthermore, the activity of 8a was 40.4-fold higher than that of imidacloprid against imidacloprid-resistant brown planthopper.