文献类型：期刊文献

英文题名：Fluorescent probes and functional materials for biomedical applications

作者：Hu, Xi-Le[1,2];Gan, Hui-Qi[1,2];Meng, Fan-De[1,2];Han, Hai-Hao[1,2];Shi, De-Tai[7];Zhang, Shu[4,5];Zou, Lei[1,2];He, Xiao-Peng[1,2];James, Tony D.[3,6]

机构：[1]East China Univ Sci & Technol, Sch Chem & Mol Engn, Feringa Nobel Prize Scientist Joint Res Ctr, Key Lab Adv Mat, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Sch Chem & Mol Engn, Feringa Nobel Prize Scientist Joint Res Ctr, Joint Int Res Lab Precis Chem & Mol Engn, Shanghai 200237, Peoples R China;[3]Univ Bath, Dept Chem, Bath BA2 7AY, Avon, England;[4]Fudan Univ, Minist Educ, Zhongshan Hosp, Liver Canc Inst, Shanghai 200032, Peoples R China;[5]Fudan Univ, Minist Educ, Key Lab Carcinogenesis & Canc Invas, Shanghai 200032, Peoples R China;[6]Henan Normal Univ, Sch Chem & Chem Engn, Xinxiang 453007, Henan, Peoples R China;[7]Jingdezhen Ceram Inst, Sch Mat Sci & Engn, Jingdezhen 333403, Peoples R China

年份：2022

卷号：16

期号：10

起止页码：1425

外文期刊名：FRONTIERS OF CHEMICAL SCIENCE AND ENGINEERING

收录：;EI(收录号：20222112135747);WOS:【SCI-EXPANDED(收录号:WOS:000797316100001)】；

基金：The authors thank the National Natural Science Foundation of China (Grant Nos. 21907030 and 22108077) and the International Cooperation Program of Shanghai Science and Technology Committee (Grant No. 19410712600). De-Tai Shi would like to thank the Natural Science Foundation of Jiangxi (Grant No. 20161BAB213067) and the Scientific Research Fund of Jiangxi Provincial Education Department (Grant No. GJJ170807). Tony D. James wishes to thank the Royal Society for a Wolfson Research Merit Award and the Open Research Fund of the School of Chemistry and Chemical Engineering, Henan Normal University for support (Grant No. 2020ZD01).

语种：英文

外文关键词：fluorescent probes; imaging; cell; biomedicine; biomolecules

摘要：Due to their simplicity in preparation, sensitivity and selectivity, fluorescent probes have become the analytical tool of choice in a wide range of research and industrial fields, facilitating the rapid detection of chemical substances of interest as well as the study of important physiological and pathological processes at the cellular level. In addition, many long-wavelength fluorescent probes developed have also proven applicable for in vivo biomedical applications including fluorescence-guided disease diagnosis and theranostics (e.g., fluorogenic prodrugs). Impressive progresses have been made in the development of sensing agents and materials for the detection of ions, organic small molecules, and biomacromolecules including enzymes, DNAs/RNAs, lipids, and carbohydrates that play crucial roles in biological and disease-relevant events. Here, we highlight examples of fluorescent probes and functional materials for biological applications selected from the special issues "Fluorescent Probes" and "Molecular Sensors and Logic Gates" recently published in this journal, offering insights into the future development of powerful fluorescence-based chemical tools for basic biological studies and clinical translation.