文献类型：期刊文献

英文题名：Rapid and sensitive in-situ detection of polar antibiotics in water using a disposable Ag-graphene sensor based on electrophoretic preconcentration and surface-enhanced Raman spectroscopy

作者：Li, Yuan-Ting[1,2];Qu, Lu-Lu[1,2];Li, Da-Wei[1,2];Song, Qi-Xia[1,2];Fathi, Farkhondeh[1,2];Long, Yi-Tao[1,2]

机构：[1]E China Univ Sci & Technol, State Key Lab Bioreactor Engn, 130 Meilong Rd, Shanghai 200237, Peoples R China;[2]E China Univ Sci & Technol, Dept Chem, Shanghai 200237, Peoples R China

年份：2013

卷号：43

期号：1

起止页码：94

外文期刊名：BIOSENSORS & BIOELECTRONICS

收录：;EI(收录号：20130215880829);WOS:【SCI-EXPANDED(收录号:WOS:000316525300017)】；

基金：We greatly appreciate the support of the National Science Fund for Distinguished Young Scholars (21125522), the National Natural Science Foundation of China (91027035 and 21007015), the Fundamental Research Funds for the Central Universities (WK1013002), Shanghai Pujiang Program Grant of China (12JC1403500), the State Key Laboratory of Chemical Engineering (SKL-ChE-11C01), and Key Laboratory of Specialty Fiber Optics and Optical Access Networks (SKLSFO2011-02).

语种：英文

外文关键词：Polar antibiotics; Disposable Ag-graphene sensor; Electrophoretic preconcentration; Surface-enhanced Raman spectroscopy; Rapid in-situ detection

摘要：A disposable Ag-graphene sensor was developed for rapid and sensitive in-situ detection of polar antibiotics in water using electrophoretic preconcentration (EP) and surface-enhanced Raman spectroscopy (SERS). The Ag-graphene sensor was fabricated by depositing Ag-graphene nanocomposites synthesized through a facile one-pot method on the disposable screen-printed electrodes (SPEs) and characterized by transmission electron microscopy (TEM) and atomic force microscopy (AFM). SERS properties and detection applicability of the developed sensor were systematically investigated. It is shown that the polar antibiotics can be selectively adsorbed on the oppositely charged sensors after applying different potentials during the EP procedure, and the SERS signals of antibiotics with an effective amplification can be achieved with proper time of preconcentration. Moreover, the Ag-graphene sensor could facilitate the molecule adsorption through weak pi-pi interactions between graphene and antibiotics, further improving the sensitivity of SERS detection. Under the optimum EP conditions, the representative SEAS spectra of a mixed solution containing four different antibiotics can be obtained within 10 min, and each antibiotic is easily distinguished by its characteristic peaks with a sub-nM detection level. The results demonstrate that the proposed disposable Ag-graphene sensor based on EP-SERS can be used for rapid and sensitive in-situ detection of polar antibiotics in aqueous samples without a pre-separation step. (c) 2012 Elsevier B.V. All rights reserved.