文献类型：期刊文献

英文题名：Synthesis, characterization, and polyphenol oxidase activity of Cu^II, Mn^II, and Fe^III complexes with a N₂O₂ ligand

作者：Lu, Lijun[1];Song, Yanying[1];Liu, Hui[1];Zhang, Jingyan[1]

机构：[1]E China Univ Sci & Technol, Sch Pharm, Dept Pharmaceut Sci, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China

年份：2012

卷号：65

期号：7

起止页码：1278

外文期刊名：JOURNAL OF COORDINATION CHEMISTRY

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000304322600015)】；

基金：The authors gratefully acknowledge the financial support by the National Natural Science Foundation (Nos 31070742 and 21001044) and the State Key Laboratory of Bioreactor Engineering (No. 2060204).

语种：英文

外文关键词：Metal complexes; Catechol oxidase; Tyrosinase; Redox potential

摘要：To explore the effect of the metal center on catechol oxidase and tyrosinase activities, four complexes, Cu-2(mu-Cl)(2)(hbpg)(2) (1), [Cu-2(mu-OH2)(2)(hbpg)(2)](NO3)(2)(H2O)(2) (2), [Fe-2(mu-Cl)(2)(hbpg)(2)]Cl-2(H2O)(2) (3), and [Mn-2(mu-Cl)(2)(hbpg)(2)](H2O)(2) (4) (hbpg = N-(2-hydroxybenzyl)-N-(2-picolyl)glycine), were synthesized and characterized with elemental analysis, single-crystal X-ray diffraction, molar conductivity measurements, mass spectrometry, UV-Visible, and FT-IR spectroscopies. The X-ray crystal structural analysis indicates that 1 has a binuclear copper, coordinated with N2O2 ligands. Complementary characterizations suggested that 2, 3, and 4 have similar coordination sphere. Complex 3 exhibits much higher catechol oxidase and tyrosinase-like activity than 1, 2, and 4. The results suggested that with a similar coordination sphere, the redox potential of the metal center is critical for catalytic activity. This work provides valuable information for improving the polyphenol oxidase activity of metal complexes for phenolic degradation.