文献类型：期刊文献

英文题名：A molecular thermodynamic model for temperature- and solvent-sensitive hydrogels, application to the swelling behavior of PNIPAm hydrogels in ethanol/water mixtures

作者：Zhi, Dongyan;Huang, Yongmin[1];Han, Xia;Liu, Honglai;Hu, Ying

机构：[1]E China Univ Sci & Technol, State Key Lab Chem Engn, Shanghai 200237, Peoples R China; E China Univ Sci & Technol, Dept Chem, Shanghai 200237, Peoples R China

年份：2010

卷号：65

期号：10

起止页码：3223

外文期刊名：CHEMICAL ENGINEERING SCIENCE

收录：;EI(收录号：20101512840074);WOS:【SCI-EXPANDED(收录号:WOS:000278104100034)】；

基金：Financial support for this work was provided by the National Natural Science Foundation of China (nos. 20976044, 20736002, 20806022), the Doctoral Research Foundation sponsored by the Ministry of Education of China (Project no. 200802510008), Program for Changjiang Scholars and Innovative Research Team in University of China (Grant IRT0721) and the 111 Project of Ministry of Education of China (no. B08021).

语种：英文

外文关键词：Hydrogel; Swelling behavior; Solvent mixtures; Molecular thermodynamic model; Temperature sensitive; Solvent sensitive

摘要：The swelling curves of poly-N-isopropylacrylamide (PNIPAm) hydrogels in ethanol/water mixtures were determined. A molecular thermodynamic model for swelling behavior of temperature- and solvent-sensitive hydrogels in solvent mixtures was developed by integrating a modified multiple lattice model developed previously for the mixing term and the Flory's Gaussian chain model for the elastic term. Three energy parameters and one volume parameter are included in this model for gel/solvent mixtures systems. Three of the four parameters can be determined from the swelling behavior of hydrogels in pure solvents. The energy parameter measuring the interaction between the two solvents is adjustable and expressed as a quadratic form of the inverse temperature. The calculated results for the swelling curves of PNIPAm hydrogels in ethanol/water mixtures at different temperatures are in good agreement with the experiments. In addition, the equilibrium concentrations of solvent mixtures inside and outside hydrogels can be predicted by this model, which is important for the application of hydrogels. (C) 2010 Elsevier Ltd. All rights reserved.