文献类型：期刊文献

英文题名：An integrated current measurement system for nanopore analysis

作者：Gao, Rui[1];Ying, Yi-Lun[1];Yan, Bing-Yong[2];Long, Yi-Tao[1]

机构：[1]E China Univ Sci & Technol, Dept Chem, Key Lab Adv Mat, Shanghai 200237, Peoples R China;[2]E China Univ Sci & Technol, Sch Informat Sci & Engn, Shanghai 200237, Peoples R China

年份：2014

卷号：59

期号：35

起止页码：4968

外文期刊名：CHINESE SCIENCE BULLETIN

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000344861500009)】；

基金：This work was supported by the National Natural Science Foundation of China (21327807). Y.-T. Long is grateful for funds from the National Science Fund for Distinguished Young Scholars of China (21125522).

语种：英文

外文关键词：Nanopore analysis; Current amplification; A/D convertor; Ultralow current detection

摘要：Nanopore-based techniques have attracted increasing attention as a unique tool for single-molecule analysis. To accurately detect individual motions of each single molecule, nanopore techniques are used to develop an ultrasensitive current measurement system. This work proposes an integrated current measurement system containing an amplifier system and a current signal acquisition system with a high current resolution and a high temporal resolution for nanopore analysis. The exploration and achievements in instrument and signal processing endow nanopore techniques with reliability, affordability, and portability, which make a great leap toward its real applications.