文献类型：期刊文献

英文题名：Borondipyrromethene-derived Cu2+ sensing chemodosimeter for fast and selective detection

作者：Zhao, Chunchang[1]; Feng, Peng[1]; Cao, Jian[1]; Wang, Xuzhe[1]; Yang, Yang[1]; Zhang, Yulin[1]; Zhang, Jinxing[1]; Zhang, Yanfen[1]

机构：[1] Key Laboratory for Advanced Materials, Institute of Fine Chemicals, East China University of Science and Technology, Shanghai 200237, China

年份：2012

卷号：10

期号：15

起止页码：3104

外文期刊名：Organic and Biomolecular Chemistry

收录：EI(收录号：20121314910872)

语种：英文

外文关键词：Esters - Fluorescence

摘要：Here, we report a new Cu2+-selective fluorescent turn-on probe BODIPY-EP, in which the 2-pyridinecarboxylic acid is connected to a 6-hydroxyindole-based BODIPY platform through an ester linkage. The ester bond of BODIPY-EP is selectively hydrolyzed by the reaction with Cu2+ under mild and neutral conditions to generate BODIPY-OH, showing strong characteristic fluorescence of BODIPY-OH. The favorable features of BODIPY-EP towards Cu2+ include fast response, large fluorescence enhancement and high selectivity. We further demonstrated that the membrane-permeable probe reacts with intracellular Cu2+ and exhibits bright fluorescence in living cells. ? The Royal Society of Chemistry 2012.