文献类型：期刊文献

英文题名：A near-infrared xanthene-based fluorescent probe for selective detection of hydrazine and its application in living cells

作者：Guo, Shao-Hua[1,2];Leng, Tao-Hua[3];Wang, Kai[1,2];Shen, Yong-Jia[1,2];Wang, Cheng-Yun[1,2]

机构：[1]East China Univ Sci & Technol, Sch Chem & Mol Engn, Key Lab Adv Mat, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Sch Chem & Mol Engn, Inst Fine Chem, Shanghai 200237, Peoples R China;[3]Shanghai Inst Qual Inspect & Tech Res, Natl Food Qual Supervis & Inspect Ctr Shanghai, Shanghai, Peoples R China

年份：2019

卷号：223

外文期刊名：SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

收录：;EI(收录号：20192907190179);WOS:【SCI-EXPANDED(收录号:WOS:000489293900015)】；

基金：The authors are grateful to financial support from Natural Science Foundation of Shanghai (16ZR1408000) and the National Natural Science Foundation of China (No. 21576087).

语种：英文

外文关键词：Near-infrared fluorescence; Hydrazine; Bioimaging; High selectivity

摘要：Developing fluorescent probes for selective determination of the toxic and carcinogenic hydrazine are pretty significant. Herein, a rhodamine dye coupled to naphthalene was selected as a near-infrared fluorophore and acetyl group as a trigger unit for hydrazine sensing with a Stokes shifts of 62 nm. The probe showed about 77-fold NIR fluorescence enhancement in the presence of hydrazine. In addition, the detection limit was as low as 3.4 ppb, and the fluorescence intensity at 654 nm showed a satisfactory linearity with the concentration range of hydrazine from 0 to 120 mu M. More importantly, the practical utility of probe has been successfully proved through the fluorescence bioimaging of hydrazine in living cells with low cytotoxicity and quantitative N-2 H-4 detection in environmental water samples. (C) 2019 Elsevier B.V. All rights reserved.