文献类型：期刊文献

英文题名：CO2-Promoted Direct Oxygenation of Benzylic sp3 C-H Bonds Using Sodium Chlorite

作者：Liu, Chaoyang[1];Xu, Ning[1];Zhang, Lanling[1];Gu, Wenjing[1];Chu, Changhu[1];Ma, Lei[1]

机构：[1]East China Univ Sci & Technol, Engn Res Ctr Pharmaceut Proc Chem, Sch Pharm, Minist Educ,Shanghai Key Lab New Drug Design, Shanghai 200237, Peoples R China

年份：2025

卷号：90

期号：45

起止页码：16112

外文期刊名：JOURNAL OF ORGANIC CHEMISTRY

收录：;EI(收录号：20255019678114);WOS:【SCI-EXPANDED(收录号:WOS:001606704400001)】；

基金：This work was supported by the National Natural Science Foundation of China (Grant 82373739) and Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism (Shanghai Municipal Education Commission).

语种：英文

外文关键词：Oxygenation - pH - Sodium

摘要：Utilizing inexpensive and environmentally benign sodium chlorite, a CO2-promoted oxidation of benzylic sp3 C-H bonds has been developed. In this process, CO2 acts as an effective pH regulator, enabling the reaction to proceed under safe, mild conditions. Three classes of benzylic substrates, amines, ethers, and alkylarenes, can be effectively oxidized to their corresponding carbonyl products.