文献类型：期刊文献

英文题名：Photoinduced drug release from thermosensitive AuNPs-liposome using a AuNPs-switch

作者：An, Xueqin[1,2];Zhang, Fan[2];Zhu, Yinyan[2];Shen, Weiguo[1]

机构：[1]E China Univ Sci & Technol, Sch Chem & Mol Engn, Shanghai 200237, Peoples R China;[2]Nanjing Normal Univ, Jiangsu Key Lab Biofunct Mat, Coll Chem & Environm Sci, Nanjing 210097, Jiangsu, Peoples R China

年份：2010

卷号：46

期号：38

起止页码：7202

外文期刊名：CHEMICAL COMMUNICATIONS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000282004900034)】；

基金：This work is financially supported by the National Nature Science Foundation of China (20673059, 20573056 and 21073063), the Nature Science Keystone Foundation of Shanghai (08jc1408100), and the Fundamental Research Funds for the Central Universities, China (No. WK0913002).

语种：英文

摘要：A thermosensitive liposome with embedded AuNPs in a bilayer was prepared using supercritical CO(2). The AuNPs-liposome can absorb a certain wavelength light, convert optical energy into heat, induce phase transition, and release drug. The results show that drug release from the liposome is due to the photothermic effects inducing phase transition of the liposome rather than destruction of the liposome structure.