文献类型：期刊文献

英文题名：An Antibacterial and Antioxidant Food Packaging Film Based on Amphiphilic Polypeptides-Resveratrol-Chitosan

作者：Zhang, Yu[1,2];Song, Wenliang[3];Mao, Shina[1];Qian, Yiduo[1];Gui, Qiudi[1];Du, Jianzhong[4,5,6]

机构：[1]Shanghai Univ Med & Hlth Sci, Sch Pharm, Shanghai Key Lab Mol Imaging, Shanghai 201318, Peoples R China;[2]Fudan Univ, State Key Lab Mol Engn Polymers, Shanghai 200433, Peoples R China;[3]Univ Shanghai Sci & Technol, Sch Mat & Chem, Shanghai 200093, Peoples R China;[4]Tongji Univ, Shanghai Peoples Hosp 4, Res Inst Brain & Brain Intelligence, Sch Med,Shanghai Key Lab Anesthesiol & Brain Funct, Shanghai 200434, Peoples R China;[5]Tongji Univ, Sch Mat Sci & Engn, Dept Polymer Mat, 4800 Caoan Rd, Shanghai 201804, Peoples R China;[6]East China Univ Sci & Technol, Sch Mat Sci & Engn, Shanghai 200237, Peoples R China

年份：2025

卷号：21

期号：5

外文期刊名：SMALL

收录：;EI(收录号：20245117533396);WOS:【SCI-EXPANDED(收录号:WOS:001376093100001)】；

基金：Y.Z. and W.S. contributed equally to this work. This work was supported by the Shanghai Sailing Program (22YF1417700), the Open Research Fund Program of the State Key Laboratory of Molecular Engineering of Polymers (Fudan University, K2023-13), the Open Research Fund Program of the Shanghai Key Laboratory of Molecular Imaging (Shanghai University of Medicine and Health Sciences, KFKT-2023-24), the Scientific Research Foundation of the Shanghai University of Medicine and Health Sciences (SSF-22-07-02), the National Natural Science Foundation of China (21925505 and 22335005), and the Innovation Program of Shanghai Municipal Education Commission (2023ZKZD28). Authors sincerely appreciate Mark Berndt from the University of California, Riverside, for his meticulous proofreading of the manuscript. The authors thank BNCC (BeNa Culture collection) for the products of BNCC133264 and BNCC186335.

语种：英文

外文关键词：amphiphilic polypeptides; antibacterial activity; chitosan; food packaging; resveratrol

摘要：Antimicrobial and antioxidant packaging films play a crucial role in extending food shelf life, maintaining quality, and enhancing safety by inhibiting microbial growth and slowing oxidation processes. However, most commercial preservative films suffer from limited antimicrobial and antioxidant properties. Moreover, these films are made from petroleum-based materials that degrade into microplastics, resulting in environmental contamination and potential health risks for humans. Herein, an antibacterial and antioxidant food packaging film (CS-SAP@R) is developed by integrating star-shaped amphiphilic polypeptides (SAP) and resveratrol (R) into the chitosan (CS) matrix. The incorporation of SAP not only effectively addresses the existing compatibility issues between the highly hydrophobic resveratrol and water-soluble CS film, but also significantly enhances the antimicrobial properties of CS. Additionally, the well-integrated resveratrol molecules endow the film with superior antioxidant properties. Furthermore, CS-SAP@R has achieved bacterial killing rates of 97.31% against E. coli and 99.05% against S. aureus. The enhanced characteristics of the CS-SAP@R film contribute to its exceptional preservation performance, effectively extending the shelf life of perishable products by approximate to 3 days when stored at 4 degrees C. These remarkable attributes underscore the benefits of polypeptide-based biopolymers and demonstrate the potential applicability of the CS-SAP@R film in effectively safeguarding perishable products.