文献类型：期刊文献

英文题名：One-pot synthesis of polyfunctionalized 4H-pyran derivatives bearing fluorochloro pyridyl moiety

作者：Ye, Zhenjun[1];Xu, Renbo[1];Shao, Xusheng[1];Xu, Xiaoyong[1];Li, Zhong[1]

机构：[1]E China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China

年份：2010

卷号：51

期号：38

起止页码：4991

外文期刊名：TETRAHEDRON LETTERS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000281626100018)】；

基金：This work was financial supported by National Basic Research Program of China (973 Program, 2010CB126106), National High Technology Research and Development Program of China (863 Program, 2010AA10A204), National Science Foundation China Program Grant (20872034) and Program for New Century Excellent Talents in University (NCET070284). This work was also partly supported by Shanghai Foundation of Science and Technology (073919107, 09XD1401300, 09391911800). We thank Dr. Yucheng Gu of Syngenta at Jealott's Hill International Research Centre in the UK for proofreading of the manuscript.

语种：英文

外文关键词：4H-Pyran derivatives; Fluorochloro pyridyl; Multicomponent reactions (MCRs)

摘要：Polyfunctionalized 4H-pyran derivatives bearing fluorochloro pyridyl moiety were readily prepared in high yields via one-pot multicomponent reaction catalyzed by piperidine. This present protocol provides an efficient synthetic route to the target compounds with the characteristics of short reaction time, high yield, and easy separation of the products. (C) 2010 Elsevier Ltd. All rights reserved.