文献类型：期刊文献

英文题名：Synthesis of β-Hydroxysulfides via Multi-Component Cascade Hydroxysulfenylation of Styrenes with NH4SCN and Water under Transition-metal-free Conditions

作者：Liu, Xian[1];Hao, Liqiang[1];Wang, Yangyang[1];Ji, Yafei[1]

机构：[1]East China Univ Sci & Technol, Engn Res Ctr Pharmaceut Proc Chem, Minist Educ, 130 Meilong Rd, Shanghai 200237, Peoples R China

年份：2024

卷号：19

期号：1

外文期刊名：CHEMISTRY-AN ASIAN JOURNAL

收录：;EI(收录号：20234815120279);WOS:【SCI-EXPANDED(收录号:WOS:001109747700001)】；

基金：We are grateful to the National Natural Science Foundation of China (Project No. 21676088) for financial support.

语种：英文

外文关键词：One-pot; Hydroxysulfenylation; Styrene; Radical cascade; Transition-metal-free

摘要：Transition-mental-free multi-component hydroxysulfenylation of styrenes with NH4SCN and water to from beta-hydroxysulfides is established. The reaction mechanism proceeded via a domino reaction after a radical addition to 2-phenylimidazo[1,2-a]pyridines. This approach features a wide substrate scope and functional group compatibility, providing 34 compounds in acceptable yields.