文献类型：期刊文献

英文题名：Pyrrole- and Dihydropyrrole-Fused Neonicotinoids: Design, Synthesis, and Insecticidal Evaluation

作者：Ye, Zhenjun[1];Shi, Lina[1];Shao, Xusheng[1];Xu, Xiaoyong[1];Xu, Zhiping[1];Li, Zhong[1]

机构：[1]E China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China

年份：2013

卷号：61

期号：2

起止页码：312

外文期刊名：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

收录：;EI(收录号：20130415939208);WOS:【SCI-EXPANDED(收录号:WOS:000313933100006)】；

基金：This work was financially supported by National Basic Research Program of China (973 Program, 2010CB126100), National High Technology Research and Development Program of China (863 Program, 2011AA10A207). This work was also partly supported by National Key Technology R&D Program of China (2011BAE06B01).

语种：英文

外文关键词：Pyrrole; dihydropyrrole; neonicotinoid; nAChR

摘要：Versatile pyrrole- and dihydropyrrole-fused neonicotinoids were obtained from cyclic and non-cyclic nitroeneamines. Anhydrous aluminum chloride (AlCl3) exhibited high catalytic selectivity for the synthesis of the titled etherified compounds at room temperature and the eliminated products under reflux conditions. The target molecules have been identified on the basis of satisfactory analytical and spectral [H-1 and C-13 nuclear magnetic resonance (NMR), high-resolution mass spectrometry (HAMS), and X-ray] data. All synthesized compounds have been screened for insecticidal activity. The preliminary insecticidal activity results showed that some of the aimed compounds displayed excellent insecticidal activity against cowpea aphids (Aphis craccivora).