文献类型：期刊文献

中文题名：Synthesis, Self-assembly and pH Sensitivity of a Novel Fluorinated Triphilic Block Copolymer

英文题名：Synthesis, self-assembly and pH sensitivity of a novel fluorinated triphilic block copolymer

作者：Li, Xin-xin[1];Huo, Xiao[1];Han, Hui-jiao[1];Lin, Shao-liang[2]

机构：[1]East China Univ Sci & Technol, Sch Mat Sci & Engn, Key Lab Specially Funct Polymer Mat & Related Tec, Minist Educ, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Key Lab Adv Polymer Mat, Shanghai 200237, Peoples R China

年份：2017

卷号：35

期号：11

起止页码：1363

中文期刊名：Chinese Journal of Polymer Science

外文期刊名：CHINESE JOURNAL OF POLYMER SCIENCE

收录：CSTPCD;;EI(收录号：20212810632330);Scopus;WOS:【SCI-EXPANDED(收录号:WOS:000411900800005)】；CSCD:【CSCD2017_2018】；

基金：This work was financially supported by the National Natural Science Foundation of China (Nos. 51622301 and 51573046) and Fundamental Research Funds for the Central Universities (Nos. B14018, WD1616010 and 222201717001).

语种：英文

中文关键词：Triphilic block copolymer; Self-assembly; pH sensitivity; Fluorinated copolymer; Multi-compartment structure

外文关键词：Triphilic block copolymer; Self-assembly; pH sensitivity; Fluorinated copolymer; Multi-compartment structure

摘要：A novel fluorinated triblock copolymer incorporating 2-ethylhexyl methacrylate （EHMA）, tert-butyl methacrylate （tBMA） and 1H,1H,2H,2H-perfluorodecyl acrylate （FA） （PEHMA-b-PtBMA-b-PFA） was first synthesized using three successive reversible addition fragmentation chain transfer （RAFT） polymerization and the subsequent hydrolyzing at acidic condition. The as-fabricated triblock copolymer exhibited an interesting morphology evolution from the multi-compartment rod-like structure to spherical structure along with the addition of a selective solution. At the same time, a visible phase separation domain could be seen in the core area due to the existence of fluorocarbon segments. Furthermore, the self- assembly behavior of the triphilic copolymer at different pH was also verified by transmission electron microscopy, as well as the dynamic light scattering. These stimuli-responsive multi-compartment nanostructures may have potential applications in drug delivery.
A novel fluorinated triblock copolymer incorporating 2-ethylhexyl methacrylate (EHMA), tert-butyl methacrylate (tBMA) and 1H,1H,2H,2H-perfluorodecyl acrylate (FA) (PEHMA-b-PtBMA-b-PFA) was first synthesized using three successive reversible addition fragmentation chain transfer (RAFT) polymerization and the subsequent hydrolyzing at acidic condition. The as-fabricated triblock copolymer exhibited an interesting morphology evolution from the multi-compartment rod-like structure to spherical structure along with the addition of a selective solution. At the same time, a visible phase separation domain could be seen in the core area due to the existence of fluorocarbon segments. Furthermore, the self-assembly behavior of the triphilic copolymer at different pH was also verified by transmission electron microscopy, as well as the dynamic light scattering. These stimuli-responsive multi-compartment nanostructures may have potential applications in drug delivery.