文献类型：期刊文献

英文题名：A highly selective and sensitive fluorescence "turn-on" probe for Ag+ in aqueous solution and live cells

作者：Xu, Lin[1]; Xu, Yufang[1]; Zhu, Weiping[1]; Yang, Chunmei[1]; Han, Le[1]; Qian, Xuhong[1]

机构：[1] Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Shanghai, 200237, China

年份：2012

卷号：41

期号：24

起止页码：7212

外文期刊名：Dalton Transactions

收录：EI(收录号：20122515127655)

语种：英文

外文关键词：Binding energy - Metals - Solutions - Fluorescence spectroscopy - Metal ions - Probes - Silver compounds

摘要：A naphthalimide-based fluorescent probe, NPQ, that contains a novel receptor was successfully developed. NPQ exhibited "turn-on" fluorescence and excellent selectivity toward Ag+ in the presence of various other metal ions in aqueous solution. A series of control compounds were designed and synthesized in order to explore the photoinduced electron transfer (PET) quenching mechanism of NPQ and binding mode of NPQ with Ag+. Moreover, with the NPQ-Ag+ complex, I- was easily selectively recognized by a marked fluorescence quenching. The live cell imaging experiments demonstrate that NPQ can be used as a fluorescent probe for monitoring Ag+ in living cells. ? 2012 The Royal Society of Chemistry.