文献类型：期刊文献

英文题名：Unexpected results from the re-investigation of the Beckmann rearrangement of ketoximes into amides by using TsCl

作者：Pi, Hong-Jun[1];Dong, Jin-Dong[1];An, Na[1];Du, Wenting[1];Deng, Wei-Ping[1]

机构：[1]E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China

年份：2009

卷号：65

期号：37

起止页码：7790

外文期刊名：TETRAHEDRON

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000269475600004)】；

基金：This work was supported by the Natural Science Foundation of China (No. NSFC 20602011), the Shanghai Committee of Science and Technology (No. 06PJ14023), New Century Excellent Talents in University, the Ministry of Education, China (No. NCET-07-0283), and '111' Project (No. B07023).

语种：英文

摘要：TsCl (p-toluenesulfonyl chloride), a commercially available organosulfonyl chloride, has been widely used as a stoichiometric dehydrogenation reagent in the transformation of ketoximes into corresponding amides via the Beckmann rearrangement. It has been now found to catalyze the Beckmann rearrangement with high catalytic efficiency, converting a wide range of ketoximes into their corresponding amides under mild condition with good to excellent yields (up to 99% of yield with 1-5 mol% of catalyst loading). (C) 2009 Elsevier Ltd. All rights reserved.