文献类型：专利

英文题名：Method for preparing clarithromycin, involves subjecting (2', 4''-O-trimethylsilyl)-erythromycin A-9 (O-(1-ethoxy-1-methyl-ethyl)) oxime in methylation reaction and methylate de-protection reaction to obtain clarithromycin

作者：WU F;YANG B;ZHANG Y;ZHAO M

机构：[1]UNIV EAST CHINA SCI&TECHNOLOGY

申请号：CN102268053-A

申请日：2011-09-01

公开日：2011-12-07

语种：英文

收录：DERWENT

摘要：NOVELTY - A clarithromycin preparation method involves subjecting (2', 4''-O-trimethylsilyl)-erythromycin A-9 (O-(1-ethoxy-1-methyl-ethyl)) oxime in methylation reaction and methylate de-protection reaction to obtain clarithromycin. USE - Method for preparing clarithromycin. ADVANTAGE - The method enables preparing clarithromycin in a simple, cost-effective and environment friendly manner, and achieving industrial production.