文献类型：期刊文献

英文题名：Improved mechanical properties of hydroxyapatite/poly(ε-caprolactone) scaffolds by surface modification of hydroxyapatite

作者：Wang, Yan[1];Dai, Jing[1];Zhang, Qingchun[1];Xiao, Yan[1];Lang, Meidong[1]

机构：[1]E China Univ Sci & Technol, Sch Mat Sci & Engn, Minist Educ, Shanghai Key Lab Adv Polymer Mat,Key Lab Ultrafin, Shanghai 200237, Peoples R China

年份：2010

卷号：256

期号：20

起止页码：6107

外文期刊名：APPLIED SURFACE SCIENCE

收录：;EI(收录号：20102413004972);WOS:【SCI-EXPANDED(收录号:WOS:000278530600054)】；

基金：This research was supported by the Fundamental Research Funds for the Central Universities, the National Natural Science Foundation of China (No. 20674019), "Shu Guang" Project of Shanghai Municipal Education Commission, Shanghai Leading Academic Discipline Project (B502) and Shanghai Key Laboratory Project (08DZ2230500).

语种：英文

外文关键词：Scaffold; Poly(epsilon-caprolactone); Hydroxyapatite; Surface grafting; Mechanical property

摘要：Scaffolds comprising hydroxyapatite (HAP) or poly(epsilon-caprolactone)-grafted hydroxyapatite (g-HAP) and poly(epsilon-caprolactone) (PCL) were prepared using the thermally induced phase separation/salt leaching technique. The g-HAP nanoparticles were evaluated by Fourier Transformation Infrared Spectroscopy (FTIR) and thermal gravimetric analysis (TGA). Power X-ray Diffraction (XRD) patterns confirmed the successful grafting on the surface of HAP. The effects on mechanical strength, porosity and thermal property of scaffolds by the introduction of nanoparticles were extensively investigated. The compressive modulus of the scaffold was greatly improved by the addition of g-HAP nanoparticles. Especially the compressive modulus of the g-HAP/PCL scaffold containing 20 wt% of g-HAP was 59.4% higher than that of the corresponding HAP/PCL scaffold. (C) 2010 Elsevier B. V. All rights reserved.