文献类型：期刊文献

英文题名：Highly efficient click reaction on water catalyzed by a ruthenium complex

作者：Siyang, Hai Xiao;Liu, Hui Ling;Wu, Xin Yan;Liu, Pei Nian[1]

机构：[1]E China Univ Sci & Technol, Key Lab Adv Mat, Shanghai Key Lab Funct Mat Chem, Shanghai 200237, Peoples R China; E China Univ Sci & Technol, Inst Fine Chem, Shanghai 200237, Peoples R China

年份：2015

卷号：5

期号：6

起止页码：4693

外文期刊名：RSC ADVANCES

收录：;EI(收录号：20145200373928);WOS:【SCI-EXPANDED(收录号:WOS:000346570300097)】；

基金：This work was supported by NSFC/China, NCET (NCET-13-0798), the Basic Research Program of the Shanghai Committee of Sci. & Tech. (Project no. 13NM1400802), and the Fundamental Research Funds for the Central Universities.

语种：英文

外文关键词：Catalysts - Catalysis - Sodium Azide - Hydrocarbons

摘要：The highly efficient click reaction between terminal alkynes and azides has been achieved on water using ruthenium complex RuH2(CO)(PPh3)(3) as the catalyst, and the catalyst loading was decreased to 0.2 mol% on water from 5 mol% in organic solvent. The RuH2(CO)(PPh3)(3)/H2O system also catalyzed the one-pot click reaction of bromides, sodium azide and alkynes; in this process, azides formed in situ and then underwent a click reaction with alkynes. In both aqueous processes, 1,4-disubstituted 1,2,3-triazoles were obtained in 50-89% yield with high regioselectivity.