文献类型：期刊文献

英文题名：Multiple depositions of Ag nanoparticles on chemically modified agarose films for surface-enhanced Raman spectroscopy

作者：Zhai, Wen-Lei[1,2];Li, Da-Wei[1,2];Qu, Lu-Lu[1,2];Fossey, John S.[1,2,3];Long, Yi-Tao[1,2]

机构：[1]E China Univ Sci 4 & Technol, Key Lab Adv Mat, Shanghai 200237, Peoples R China;[2]E China Univ Sci 4 & Technol, Dept Chem, Shanghai 200237, Peoples R China;[3]Univ Birmingham, Sch Chem, Birmingham B15 2TT, W Midlands, England

年份：2012

卷号：4

期号：1

起止页码：137

外文期刊名：NANOSCALE

收录：;EI(收录号：20115114609818);WOS:【SCI-EXPANDED(收录号:WOS:000297848500018)】；

基金：This research was supported by the National Nature Science Foundation of China (91027035, 21007015), the National Science Fund for Distinguished Young Scholars (21125522), and the Fundamental Research Funds for the Central Universities (WK1013002). YTL is supported by the Program for Professor of Special Appointment (Eastern Scholar) at the Shanghai Institutions of Higher Learning. JSF thanks East China University of Science and Technology for a visiting professorship, the University of Birmingham and ERDF AWM II. The authors thank the Catalysis and Sensing for our Environment (CASE) network.

语种：英文

外文关键词：Deposition - Light transmission - Film preparation - Substrates - Cost effectiveness - Metal nanoparticles - Raman spectroscopy

摘要：A facile and cost-effective approach for the preparation of a surface-enhanced Raman spectroscopy (SERS) substrate through constructing silver nanoparticle/3-aminopropyltriethoxysilane/agarose films (Ag NPs/APTES/Agar film) on various solid supports is described. The SERS performance of the substrate was systematically investigated, revealing a maximum SERS intensity with four layers of the Ag NP deposition. The enhancement factor of the developed substrate was calculated as 1.5 x 10(7) using rhodamine 6G (R6G) as the probe molecule, and the reproducibility of the SERS signals was established. A high throughput screening platform was designed, manufactured and implemented which utilised the ability to cast agarose to assemble arrays. Quantitative analysis of 4-aminobenzoic acid (4-ABA) and 4-aminothiophenol (4-ATP) was achieved over a similar to 0.5 nM-0.1 mu M range.