文献类型：期刊文献

英文题名：Functional Polyion Complex Vesicles Enabled by Supramolecular Reversible Coordination Polyelectrolytes

作者：Zhou, Wenjuan[1,2];Wang, Jiahua[1,2];Ding, Peng[1,2];Guo, Xuhong[1,2];Stuart, Martien A. Cohen[1,2];Wang, Junyou[1,2]

机构：[1]East China Univ Sci & Technol, State Key Lab Chem Engn, 130 Meilong Rd, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Shanghai Key Lab Multiphase Mat Chem Engn, 130 Meilong Rd, Shanghai 200237, Peoples R China

年份：2019

卷号：58

期号：25

起止页码：8494

外文期刊名：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

收录：;EI(收录号：20192006939637);WOS:【SCI-EXPANDED(收录号:WOS:000476608700036)】；

基金：This work was financially supported by the Shanghai Municipal Natural Science Foundation (17ZR1440500, 17PJ1401800) and the Fundamental Research Funds for the Central Universities (222201714003).

语种：英文

外文关键词：self-assembly; electrolytes; micelles; polymers; vesicles

摘要：Reported here is a new class of PICsomes (vesicles formed by polyelectrolyte complexation) in which the anionic/neutral diblock copolymer is replaced by an anionic, reversible, supramolecular polyelectrolyte based on metal-ligand coordination. This supramolecular polyelectrolyte forms exclusively inside the wall of the assembly, and therefore self-adjusts its length to that of the cationic block provided. Moreover, the supramolecular coordination polyelectrolytes introduce new and tunable properties and functions associated with the specific metal. As a proof-of-concept Mn-based PICsomes were prepared and display high magnetic relaxivity, as well as enhanced contrast in in vitro magnetic resonance imaging tests. The simplicity of our approach, together with the new functions derived from the metal ions, demonstrates a robust strategy for the preparation of a variety of PICsomes with well-defined and tunable structures and properties.