文献类型：期刊文献

英文题名：Synthesis and characterization of new biodegradable comb-dendritic triblock copolymers

作者：Ju, Mingjie[1];Shen, Li[2];Gong, Feirong[1];Gao, Yun[1];Zhang, Weian[1]

机构：[1]E China Univ Sci & Technol, Sch Mat Sci & Engn, Key Lab Ultrafine Mat, Minist Educ, Shanghai 200237, Peoples R China;[2]Fudan Univ, Zhongshan Hosp, Shanghai Inst Cardiovasc Dis, Shanghai 200032, Peoples R China

年份：2012

卷号：61

期号：9

起止页码：1447

外文期刊名：POLYMER INTERNATIONAL

收录：;EI(收录号：20123315339113);WOS:【SCI-EXPANDED(收录号:WOS:000307310900014)】；

基金：This work was financially supported by the National Natural Science Foundation of China (nos. 21074035, 51173044 and 81000105). WZ acknowledges the Fundamental Research Funds for the Central Universities.

语种：英文

外文关键词：dumbbell-shaped triblock copolymers; ring-opening polymerization; microsphere; double emulsion

摘要：A series of well-defined dumbbell-shaped triblock copolymers consisting of linear poly(ethylene glycol) (PEG) and comb-like poly(e-caprolactone) (PCL) with varied PCL arm lengths have been synthesized via the sequential preparation of different generation terminal dendronized PEG and ring-opening polymerization of e-caprolactone. The copolymers were characterized using Fourier transform infrared, 1H NMR and 13C NMR spectroscopy and gel permeation chromatography. Differential scanning calorimetry was performed to measure the glass transition temperature, melting point and degree of crystallinity and the PEG segment and PCL segment crystallization temperatures. The crystallization of the copolymers was also studied using X-ray diffraction. The dumbbell-shaped copolymers were further used to construct microspheres using a double emulsion method. Scanning electron microscopy and dynamic light scattering results showed the size of the microspheres was about 2 to 4 mu m and the size distribution was quite narrow. Copyright (c) 2012 Society of Chemical Industry