文献类型：期刊文献

英文题名：Targeted Intracellular Production of Reactive Oxygen Species by a 2D Molybdenum Disulfide Glycosheet

作者：Ji, Ding-Kun[1,2];Zhang, Yue[1,2,3];Zang, Yi[3];Li, Jia[3];Chen, Guo-Rong[1,2];He, Xiao-Peng[1,2];Tian, He[1,2]

机构：[1]East China Univ Sci & Technol, Key Lab Adv Mat, 130 Meilong Rd, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Inst Fine Chem, Sch Chem & Mol Engn, 130 Meilong Rd, Shanghai 200237, Peoples R China;[3]Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Natl Ctr Drug Screening, 189 Guo Shoujing Rd, Shanghai 201203, Peoples R China

年份：2016

卷号：28

期号：42

起止页码：9356

外文期刊名：ADVANCED MATERIALS

收录：;EI(收录号：20163502763612);WOS:【SCI-EXPANDED(收录号:WOS:000391174600012)】；

基金：This research was supported by the 973 project (2013CB733700), the Natural Science Foundation of China (21572058, 21576088, and 81302820), the National Science and Technology Major Projects (2014ZX09507-002), the Shanghai Science and Technology Development Funds (14YF1413300), and the Shanghai Rising-Star Program (16QA1401400) (X.-P. H.). Miss Ya Kong at SIMM is warmly thanked for her help in cellular assays. Xenograft mice were kindly gifted by Prof. Xiongwen Zhang at ECNU. The use and care of experimental animals was approved by the Institutional Animal Care and Use Committee (IACUC), East China Normal University (ECNU), with the certification number of AR201404020. Cells were purchased from ATCC.

语种：英文

外文关键词：Supramolecular chemistry - Copper compounds - Layered semiconductors - Ligands - Oxygen - Self assembly - Cytology - Molybdenum disulfide - Van der Waals forces - Cells - Light scattering - Solutions

摘要：A 2D "glycosheet" based on supramolecular self-assembly between 2D MoS 2 and fl uorescent glycoligands is developed. The composite 2D material is proven suitable for targeted intracellular production of reactive oxygen species (singlet oxygen) by the sequential control of a receptor endocytosis and light irradiation.