文献类型：期刊文献

英文题名：An arginine-functionalized stationary phase for hydrophilic interaction liquid chromatography

作者：Wu, Shengjie[1];Li, Xiuling[2,3];Zhang, Feifang[1];Jiang, Ge[2];Liang, Xinmiao[1,2];Yang, Bingcheng[1]

机构：[1]E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China;[2]Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China;[3]Nantong Univ, Co Innovat Ctr Neuroregenerat, Nantong 226019, Peoples R China

年份：2015

卷号：140

期号：12

起止页码：3921

外文期刊名：ANALYST

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000355852400005)】；

基金：The research was sponsored by the National Natural Science Foundation of China (no. 21322502, 21477037). Moreover, authors thank the support from the Outstanding Young Talent Cultivation Fund of ECUST.

语种：英文

摘要：An arginine-functionalized stationary phase for hydrophilic interaction liquid chromatography (HILIC) has been prepared for the first time by clicking arginine onto silica gel. It offers an efficient separation of organic acids, nucleotides and sugars. More interestingly, it exhibited excellent selectivity and enrichment toward acidic glycopeptides, even at a ratio of 1 : 150 to non-glycopeptides.