文献类型：期刊文献

英文题名：Toxic effects of copper ion in zebrafish in the joint presence of CdTe QDs

作者：Zhang, Wei[1,2,3];Miao, Youna[1,2,3];Lin, Kuangfei[1,2,3];Chen, Lin[1,2,3];Dong, Qiaoxiang[4];Huang, Changjiang[4]

机构：[1]E China Univ Sci & Technol, State Environm Protect Key Lab Environm Risk Asse, Shanghai 200237, Peoples R China;[2]E China Univ Sci & Technol, Shanghai Key Lab Funct Mat Chem, Shanghai 200237, Peoples R China;[3]E China Univ Sci & Technol, Sch Resource & Environm Engn, Shanghai 200237, Peoples R China;[4]Wenzhou Med Coll, Zhejiang Prov Key Lab Technol & Applicat Model Or, Wenzhou 325035, Peoples R China

年份：2013

卷号：176

起止页码：158

外文期刊名：ENVIRONMENTAL POLLUTION

收录：;EI(收录号：20130916051514);WOS:【SCI-EXPANDED(收录号:WOS:000317028800021)】；

基金：This research was financially supported by the National Natural Science Foundation of China (40901148), the Science and Technology Committee Research Program of Shanghai (12DZ0502700), the Environmental Protection Science and Technology Research Program of Shanghai (2012-03), the Major State Basic Research Development Program of China (2011CB200904), and the National Forestry Public Welfare Science and Technology Research Program of China (201104088).

语种：英文

外文关键词：Quantum dots; Heavy metal; Zebrafish; Facilitated transport; Toxicological effect

摘要：Quantum dots (QDs) have strong adsorption capacity; therefore, their potential toxicity of the facilitated transport of other trace toxic pollutants when they co-exist to aquatic organisms has become a hot research topic. The lab study was performed to determine the developmental toxicities to the zebrafish after exposed to the combined pollution of Cadmium-telluride (CdTe) QDs and copper ion (Cu2+) compared to the single exposure. Our findings for the first time revealed that: 1) CdTe QDs facilitated the accumulation of Cu2+ in zebrafish, 2) the higher mortality, lower hatch rate, and more malformations can be clearly observed, 3) the diverse vascular hyperplasia, turbulence, and bifurcation of the exposed FLI-1 transgenic zebrafish larvae appeared together, 4) the synergistic effects played more important role during joint exposure. These observations provide a basic understanding of CdTe QDs and Cu2+ joint toxicity to aquatic organisms. (C) 2013 Elsevier Ltd. All rights reserved.