文献类型：会议论文

英文题名：Bioactivity and biocompatibility of Na₂O-K₂O-CaO-MgO-SrO-B₂O₃-P₂O₅ borophosphate glass

作者：Zheng, Kai[1];Yang, Shengbing[1];Liang, Wen[1];Ruessel, Christian[2]

机构：[1]E China Univ Sci & Technol, Sch Mat Sci & Engn, Res Inst Biomat, Shanghai 200237, Peoples R China;[2]Univ Jena, Otto Schott Inst, Jena, Germany

会议论文集：International Conference on Materials and Products Manufacturing Technology (ICMPMT 2011)

会议日期：OCT 28-30, 2011

会议地点：Chengdu, PEOPLES R CHINA

语种：英文

外文关键词：borophosphate; bioactivity; biocompatibility; MTT; cell test

摘要：A novel Na2O-K2O-CaO-MgO-SrO-B2O3-P2O5 borophosphate glass is prepared by melting method. The thermal properties have been examined by differential thermal analysis (DTA) and viscosity measurement. The bioactivity of the glass is measured via soaking the glass in the SBF solution at 37 degrees C for different time. The reaction of the glass in the SBF solution is characterized by XRD, FTIR and SEM. The results indicate that the carbonate hydroxyapatite deposit on the glass in less than 7 days. Cell attachment, spreading and proliferation on the glass is determined by MTT [3-(4, 5-Dimethylthiazol-2-yl)-2, 5-Diphenyltetrazolium Bromide] assay method using Human osteosarcoma MG-63 cells. The borophosphate glass fiber is also drawn and the tensile strength is measured. The results suggest the borophosphate glass has a good potential to be a scaffold material for bone tissue engineering.