文献类型：期刊文献

英文题名：A highly sensitive and selective hypochlorite fluorescent probe based on oxidation of hydrazine via free radical mechanism

作者：Cheng, Tanyu[1];Zhao, Junwei[1];Wang, Ziyun[1];An, Juzeng[1];Xu, Yufang[2];Qian, Xuhong[2];Liu, Guohua[1]

机构：[1]Shanghai Normal Univ, Dept Chem, Key Lab Resource Chem, Key Lab Rare Earth Funct Mat,Minist Educ, 100 Guilin Rd, Shanghai 200234, Peoples R China;[2]E China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab Chem Biol, State Key Lab Bioreactor Engn, 130 Meilong Rd, Shanghai 200237, Peoples R China

年份：2016

卷号：126

起止页码：218

外文期刊名：DYES AND PIGMENTS

收录：;EI(收录号：20160501864204);WOS:【SCI-EXPANDED(收录号:WOS:000370090600027)】；

语种：英文

外文关键词：Fluorescent probe; Hypochlorite; BODIPY; Oxidation; Hydrazine; Off-on

摘要：Developing fluorescent probes for selective and sensitive detection of hypochlorite has received much attention, because hypochlorite is closely related to human health. In this work, a new fluorescent probe based on dipyrromethene boron difluoride (BODIPY) fluorophore using hydrazine as detecting group for hypochlorite was synthesized and fully characterized. The reaction of the probe with sodium hypo chlorite is complete within 1 min in phosphate-buffered saline, and the fluorescence of the system significantly enhanced. The probe also exhibits admirable sensitivity and selectivity as well. The results of nuclear magnetic resonance monitoring and high-performance liquid chromatography analysis indicate that the detection process plausibly involves a free radical oxidation mechanism. (C) 2015 Elsevier Ltd. All rights reserved.