文献类型：期刊文献

英文题名：Base-mediated direct fluoroalkenylation of 2-phenyl-1,3,4-oxadiazole, benzothiazole and benzoxazole with gem-difluoroalkenes

作者：Zhang, Xuxue[1];Lin, Yingyin[1];Zhang, Juan[1];Cao, Song[1]

机构：[1]E China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China

年份：2015

卷号：5

期号：11

起止页码：7905

外文期刊名：RSC ADVANCES

收录：;EI(收录号：20150300423173);WOS:【SCI-EXPANDED(收录号:WOS:000347720900014)】；

基金：We are grateful for financial supports from the National Natural Science Foundation of China (Grant nos 21472043, 21272070), and the Key Project in the National Science & Technology Pillar Program of China in the twelth five-year plan period (2011BAE06B01-15).

语种：英文

外文关键词：Substitution reactions

摘要：Direct alpha-fluorovinylation of 2-phenyl-1,3,4-oxadiazole, benzothiazole and benzoxazole with gem-difluoroalkenes via nucleophilic vinylic substitution reaction (SNV) under the assistance of KHMDS or NaH at room temperature is described.