文献类型：期刊文献

英文题名：Carbonylative Cross-Coupling Reaction of Allylic Alcohols and Organoalanes with 1 atm CO Enabled by Nickel Catalysis

作者：Wang, Chenglong[1,2];Wu, Xianqing[1,2];Li, Haiyan[1,2];Qu, Jingping[1,2];Chen, Yifeng[1,2]

机构：[1]East China Univ Sci & Technol, Feringa Nobel Prize Scientist Joint Res Ctr, Frontiers Sci Ctr Mat & Dynam Chem, Key Lab Adv Mat,Sch Chem & Mol Engn, 130 Meilong Rd, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Feringa Nobel Prize Scientist Joint Res Ctr, Joint Int Res Lab Precis Chem & Mol Engn, Frontiers Sci Ctr Mat & Dynam Chem,Sch Chem & Mol, 130 Meilong Rd, Shanghai 200237, Peoples R China

年份：2022

卷号：61

期号：38

外文期刊名：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

收录：;EI(收录号：20223512674202);WOS:【SCI-EXPANDED(收录号:WOS:000840892000001)，CCR-EXPANDED(收录号:WOS:000840892000001)】；

基金：This work was sponsored by NSFC/China (22171079), Natural Science Foundation of Shanghai (21ZR1480400), Shanghai Rising-Star Program (20QA1402300), Shanghai Municipal Science and Technology Major Project (Grant No.2018SHZDZX03), the Program of Introducing Talents of Discipline to Universities (B16017), the Fundamental Research Funds for the Central Universities and the China Postdoctoral Science Foundation (2021M701197). The authors thank Research Center of Analysis and Test of East China University of Science and Technology for the help on NMR analysis.

语种：英文

外文关键词：Atmospheric pressure - Catalysis - Ketones - Nickel - Nickel compounds

摘要：A nickel-catalyzed three-component carbonylative cross-coupling reaction of allylic alcohols and organoalanes with CO at atmospheric pressure is reported, enabling the expedient formation of beta,gamma-unsaturated ketones with broad scope. Particularly, the chemoselective allylic carbonylation of diols further highlights the practicability of this protocol. The leverage of organoalanes as both the coupling components and the activators for the alcohol functionalization is crucial for this method, thus no extraneous activators are required.