文献类型：期刊文献

英文题名：Approaching Dynamic Behaviors of Life through Systems Chemistry

作者：Gu, Ruirui[1];Larsen, Kim Lambertsen[2];Wang, Ali[3];Tan, Junjun[3]

机构：[1]East China Univ Sci & Technol, Key Lab Adv Mat,Joint Int Res Lab Precis Chem & Mo, Frontiers Sci Ctr Materiobiol & Dynam Chem,Inst Fi, Sch Chem & Mol Engn,Feringa Nobel Prize Scientist, 130 Meilong Rd, Shanghai, Peoples R China;[2]Aalborg Univ, Dept Chem & Biosci, Sect Chem Sci & Engn, Fredrik Bajers Vej 7H, Aalborg, Denmark;[3]Univ Copenhagen, Dept Chem, Sect Biol Chem, Univ Pk 5, Copenhagen, Denmark

年份：2025

卷号：31

期号：2

外文期刊名：CHEMISTRY-A EUROPEAN JOURNAL

收录：;EI(收录号：20244717412820);WOS:【SCI-EXPANDED(收录号:WOS:001356881300001)】；

基金：Ruirui Gu acknowledges financial support from National Natural Science Foundation of China in the grant agreement n degrees 22205064 and Shanghai Pujiang Program in the grant agreement n degrees 22PJ1402200. Junjun Tan acknowledges financial support from European Union's Horizon 2020 Research and Innovation program for the Marie Sklodowska Curie Individual Fellowship in the grant agreement n degrees 101031072 and Novo Nordisk Foundation New Exploratory Research and Discovery (NERD) Program in the grant agreement n degrees NNF22OC0075972.

语种：英文

外文关键词：Systems chemistry; Self-replication; Dynamic Combinatorial Chemistry; Chemically fueled assemblies; Synthetic life

摘要：The intricate interplay of metabolic reactions and molecular assembly in living systems enables spatiotemporally organization and gives rise to diverse dynamic behaviors that characterize life. Over the last decades, research efforts have increasingly focused on replicating the remarkable properties and characteristics of living systems, driving the rapid growth of systems chemistry. This young discipline which generally studies interacting molecular networks and emergent system-level properties, behaviors, and functions, offers new concepts and tools to tackle the complexity of life. In this review paper, we have explored seminal research and recent advancements in recreating dynamic behaviors of life with systems chemistry. We believe that the recreation of the dynamic behaviors of life through systems chemistry would set the initial steps to obtain synthetic life de novo.