文献类型：期刊文献

英文题名：Forster resonance energy transfer (FRET)-based small-molecule sensors and imaging agents

作者：Wu, Luling[1,2,3];Huang, Chusen[1,2,3];Emery, Ben P.[3];Sedgwick, Adam C.[4];Bull, Steven D.[3];He, Xiao-Peng[5,6];Tian, He[5,6];Yoon, Juyoung[7];Sessler, Jonathan L.[4];James, Tony D.[1,2,3]

机构：[1]Shanghai Normal Univ, Dept Chem, Shanghai Key Lab Rare Earth Funct Mat, Educ Minist,Key Lab Resource Chem, 100 Guilin Rd, Shanghai 200234, Peoples R China;[2]Shanghai Normal Univ, Dept Chem, Shanghai Municipal Educ Comm Key Lab Mol Imaging, 100 Guilin Rd, Shanghai 200234, Peoples R China;[3]Univ Bath, Dept Chem, Bath BA2 7AY, Avon, England;[4]Univ Texas Austin, Dept Chem, 105 E 24th St A5300, Austin, TX 78712 USA;[5]East China Univ Sci & Technol, Feringa Nobel Prize Scientist Joint Res Ctr, Sch Chem & Mol Engn, Key Lab Adv Mat, 130 Meilong Rd, Shanghai 200237, Peoples R China;[6]East China Univ Sci & Technol, Feringa Nobel Prize Scientist Joint Res Ctr, Sch Chem & Mol Engn, Joint Int Res Lab Precis Chem & Mol Engn, 130 Meilong Rd, Shanghai 200237, Peoples R China;[7]Ewha Womans Univ, Dept Chem & Nano Sci, Seoul 120750, South Korea

年份：2020

卷号：49

期号：15

起止页码：5110

外文期刊名：CHEMICAL SOCIETY REVIEWS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000555535500012)】；

基金：LW wishes to thank China Scholarship Council and The University of Bath for supporting his PhD work in the UK. BE, SDB and TDJ would like to thank the EPSRC and The University of Bath for funding. TDJ wishes to thank the Royal Society for a Wolfson Research Merit Award. CH thanks the National Natural Science Foundation of China (Grants 21672150, 21302125), Alexander von Humboldt Foundation (AvH), Shanghai RisingStar Program (19QA1406400), Shanghai Engineering Research Center of Green Energy Chemical Engineering (18DZ2254200), and Program for Changjiang Scholars and Innovative (IRT_16R49). XPH, HT thank the Natural Science Foundation of China (No. 21788102, 21722801 and 91853201), Shanghai Municipal Science and Technology Major Project (2018SHZDZX03), the National Key Sci-Tech Special Projects of Infection Diseases of China (2018ZX10732202) and the international cooperation program of Shanghai Science and Technology Committee (17520750100). JY acknowledges a grant from the National Creative Research Initiative programs of the National Research Foundation of Korea (NRF) funded by the Korean government (MSIP) (No. 2012R1A3A2048814). JLS thanks the National Institutes of Health (R01 GM103790) and the Robert A. Welch Foundation (F-0018) for support of the work carried out in Austin.

语种：英文

摘要：In this tutorial review, we will explore recent advances in the construction and application of Forster resonance energy transfer (FRET)-based small-molecule fluorescent probes. The advantages of FRET-based fluorescent probes include: a large Stokes shift, ratiometric sensing and dual/multi-analyte responsive systems. We discuss the underlying energy donor-acceptor dye combinations and emphasise their applications for the detection or imaging of cations, anions, small neutral molecules, biomacromolecules, cellular microenvionments and dual/multi-analyte responsive systems.