文献类型：期刊文献

英文题名：Development of a bioactive chitosan HPMC-based membrane with tea polyphenols encapsulated in β-cyclodextrin as an effective enhancement

作者：Song, Jinxing[1];Feng, Huafeng[2];Wu, Mengqi[1];Chen, Linxiao[1];Xia, Wei[1];Zhang, Wenqing[1]

机构：[1]East China Univ Sci & Technol, Sch Chem & Mol Engn, Shanghai 200237, Peoples R China;[2]Shanghai Business Sch, Dept Food Sci, Shanghai 200235, Peoples R China

年份：2021

卷号：27

外文期刊名：MATERIALS TODAY COMMUNICATIONS

收录：;EI(收录号：20211810306812);WOS:【SCI-EXPANDED(收录号:WOS:000683051700006)】；

基金：This work was supported by the National Key R&D Program of China-Research on the Restoration and Protection of Typical Fragile Ecology (2016YFC0501000).

语种：英文

外文关键词：Chitosan antibacterial membrane; HPMC; Tea polyphenols; Encapsulation

摘要：Biodegradable membranes of chitosan and its composite with other natural polymers provide a promising solution for biomaterials. To further improve the antibacterial activities of chitosan (CS)/hydroxypropyl methyl cellulose (HPMC) membrane, natural extracts tea polyphenols (TP) were employed in this work. And TP was encapsulated by beta-cyclodextrin (CD) beforehand to improve its compatibility with HPMC. To our knowledge, it's the first time ever reported to use CD encapsulated TP in CS/HPMC membranes. And variety characterization results such as Fourier transform infrared spectroscopy (FTIR), ultraviolet spectra (UV) and dynamic light scattering (DLS) showed that TP had successfully encapsulated with CD. After the solvent blending of CS/HPMC and CDTP, CS/HPMC/CDTP membrane was prepared by a casting method and exhibited good toughness and tensile strength. Finally, bacterial inhibitive rate and inhibition zones of the membrane with E. coli and S. aureus proved the enhanced antibacterial as expected. And the morphology of the bacteria was observed to estimate the possible interaction approach of materials and bacteria. The novel biodegradable membrane can be used for antibacterial coating application.