文献类型：期刊文献

英文题名：Construction of functionalized naphtho[2,1-c]chromene scaffolds by Diels-Alder reaction using benzyne as dienophiles

作者：Lan, Chuanlin[1,2];Wang, Yingyi[1,2];Sha, Feng[1,2];Wu, Xinyan[1,2];Cui, Yian[1,2];Zheng, Yi[1,2]

机构：[1]East China Univ Sci & Technol, Sch Chem & Mol Engn, Key Lab Adv Mat, Meilong Rd 130, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Inst Fine Chem, Sch Chem & Mol Engn, Meilong Rd 130, Shanghai 200237, Peoples R China

年份：2025

卷号：155

外文期刊名：TETRAHEDRON LETTERS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:001392613500001)，CCR-EXPANDED(收录号:WOS:001392613500001)】；

基金：We are grateful for the financial support from Shanghai Zhuodao Investment Management Co., Ltd.

语种：英文

外文关键词：Chromene; Benzyne; Diels-Alder reaction; Kobayashi's aryne precursor; Aromatization

摘要：In this study, a direct synthetic methodology for the construction of dihydronaphtho[2,1-c]chromene scaffold derivatives has been developed. Via the benzyne-participating Diels-Alder route, the naphtho[2,1-c]chromene skeleton possessing promising biological activity could be efficiently furnished under mild conditions.