文献类型：期刊文献

英文题名：Silk Fibroin Hydrogel for Pulse Waveform Precise and Continuous Perception

作者：Yan, Yingmei[1];Deng, Weijun[2];Xie, Du[1];Hu, Jing[1,3]

机构：[1]Shanghai Inst Technol, Sch Perfume & Aroma Technol, Shanghai 201418, Peoples R China;[2]Shanghai Inst Technol, Sch Chem & Environm Engn, Shanghai 201418, Peoples R China;[3]East China Univ Sci & Technol, Sch Chem Engn, State Key Lab Chem Engn, Shanghai 200237, Peoples R China

年份：2025

卷号：14

期号：4

外文期刊名：ADVANCED HEALTHCARE MATERIALS

收录：;EI(收录号：20245217576093);WOS:【SCI-EXPANDED(收录号:WOS:001380709900001)】；

基金：Y.Y. and W.D. share the first authorship and contributed equally to this work. The authors thank Lu, L. from Bengbu Medial University and Deng, Y. from Anhui Medical University Suzhou Municipal Hospital for helpful discussion. This work is supported by National Natural Science Foundation of China (22278268, 22078196 and 22478246), Shanghai Shuguang Talent Project (19SG52) and Shanghai Natural Science Foundation (22ZR1460400).

语种：英文

外文关键词：cardiovascular disease; environmental stable; palpation; pulse waveform; silk fibroin hydrogel

摘要：Precise and continuous monitoring of blood pressure and cardiac function is of great importance for early diagnosis and timely treatment of cardiovascular diseases. The common tests rely on on-site diagnosis and bulky equipments, hindering early diagnosis. The emerging hydrogels have gained considerable attention in skin bioelectronics by virtue of the similarities to biological tissues and versatility in mechanical, electrical, and biofunctional engineering. However, hydrogels should overcome intrinsic issues such as poor mechanical strength, easy dehydration and freezing, weak adhesiveness and self-recovery, severely limiting their precision and reliability in practical applications. Here, silk fibroin hydrogels are developed as resistive sensors for pulse waveform monitoring. The silk fibroin hydrogel is simultaneously transparent, extremely stretchable, extra tough, adhesive, printable, and environmentally endurable. The silk fibroin hydrogel is also conductive with high sensitivity, short self-healing time, highly repeatable and reliable response, meeting the requirements for wearable sensors for continuous monitoring. The sensors with silk fibroin hydrogel present high-quality and stable waveforms of radical and brachial pulses with high precision and rich features, providing physiological signals of blood pressure and cardiac function. The sensors are promising for personalized health management, daily monitoring and timely diagnosis.