文献类型：期刊文献

英文题名：Biocatalytic synthesis of (R)-(-)-mandelic acid from racemic mandelonitrile by a newly isolated nitrilase-producer Alcaligenes sp ECU0401

作者：He, Yu Cai; Xu, Jian He; Xu, Yi; Ouyang, Li Ming; Pan, Jiang

机构：[1]E China Univ Sci & Technol, Lab Biocatalysis & Bioproc, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China

年份：2007

卷号：18

期号：6

起止页码：677

外文期刊名：CHINESE CHEMICAL LETTERS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000247449100016)，CCR-EXPANDED(收录号:WOS:000247449100016)】；

语种：英文

外文关键词：mandelonitrile; nitrilase; (R)-(-)-mandelic acid; screening; Alcaligenes sp ECU0401

摘要：By using acetonitrile as the sole nitrogen source, a microbial strain with high nitrilase activity, named as Alcaligenes sp. ECU0401, was newly isolated from soil, which could enantioselectively transform racemic mandelonitrile into (R)-(-)-mandelic acid, with an enantiomeric excess of > 99.9%. (C) 2007 Ran He Xu. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.