文献类型：期刊文献

英文题名：Single-Step Total Fractionation of Single-Wall Carbon Nanotubes by Countercurrent Chromatography

作者：Zhang, Min[1,2];Khripin, Constantine Y.[3];Fagan, Jeffrey A.[3];McPhie, Peter[4];Ito, Yoichiro[2];Zheng, Ming[3]

机构：[1]E China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab New Drug Design, Shanghai 200237, Peoples R China;[2]NHLBI, Lab Bioseparat Technol, Biochem & Biophys Ctr, NIH, Bethesda, MD 20892 USA;[3]NIST, Mat Sci & Engn Div, Gaithersburg, MD 20899 USA;[4]NIDDK, Lab Biochem & Genet, NIH, Bethesda, MD 20892 USA

年份：2014

卷号：86

期号：8

起止页码：3980

外文期刊名：ANALYTICAL CHEMISTRY

收录：;EI(收录号：20141717621593);WOS:【SCI-EXPANDED(收录号:WOS:000334658000044)】；

语种：英文

外文关键词：Liquid chromatography - Chirality - Mixtures - Sodium dodecyl sulfate - Sulfur compounds - Single-walled carbon nanotubes (SWCN) - Yarn - Solvent extraction

摘要：Development of simple processes to fractionate synthetic mixtures of single-wall carbon nanotubes (SWCNTs) into individual species is crucial to many applications. Existing methods for single-chirality SWCNT purification are cumbersome, often requiring multiple steps and different conditions for different species. Here, we report a method to achieve total fractionation of a synthetic SWCNT mixture by countercurrent chromatography, resulting in purification of many single-chirality SWCNT species in a single run. This method is based on a tunable partition of sodium deoxycholate dispersed SWCNTs in a polyethylene glycol/dextran aqueous two-phase system. By running the mobile phase with 0.02% of sodium deoxycholate and a gradient of sodium dodecyl sulfate from 0.1% to 0.7% (w/w), we observe clear diameter-dependent elution, with similar to 90% total recovery. Among all the fractions collected, a number of them are enriched in single-chirality (9,4), (7,5), (7,6), (8,3), (6,5) species, while most of the remaining ones contain no more than 2-3 major species. We also observe strong (n,m)-dependent elution peak width due to the enantiomer-resolved partition. These results demonstrate countercurrent chromatography (CCC) as an effective way to obtain high purity (n, m) species, and suggest the potential of CCC as an analytical tool for chirality distribution mapping of synthetic SWCNT mixtures.