文献类型：期刊文献

中文题名：一种大孔吸附树脂的合成及在红霉素提取中的应用

英文题名：Synthesis of a macroporous adsorption resin and its application to erythromycin extraction

作者：陈骏[1];宁方红[1];张志丕[2];刘坐镇[1];邬行彦[1]

机构：[1]华东理工大学生物反应器工程国家重点实验室,上海200237;[2]上海市浦东新区环境保护监测站,上海201200

年份：2002

卷号：27

期号：5

起止页码：270

中文期刊名：中国抗生素杂志

外文期刊名：Chinese Journal of Antibiotics

收录：CSTPCD;;Scopus;北大核心:【北大核心2000】；CSCD:【CSCD2011_2012】；

语种：中文

中文关键词：二乙烯苯;大孔吸附树脂;红霉素;提取

外文关键词：Divinylbenzene; Macroporous adsorption resin; Erythromycin; Extraction

摘要：以高含量工业级二乙烯苯悬浮聚合 ,合成了一系列大孔吸附树脂 ,从中筛选到一种树脂PT4 ,其对红霉素的吸附性能接近对红霉素吸附性能好的市售进口树脂AmberliteXAD 16。同时研究了用大孔吸附树脂提取红霉素的方法 ,包括吸附树脂和洗脱剂的筛选 ,吸附条件和解吸条件的考察。确定了使用PT4 树脂在pH9.2 ,流速 4BV/h的条件下对红霉素滤液的动态吸附量为 12 .2× 10 4 μ/g湿树脂 ,采用乙酸丁酯洗脱 ,洗脱液流速为 0 .5BV/h、2 .5BV洗脱液情况下洗脱率为 92 %。
A series of macroporous adsorption resins were synthesized by suspension polymerization of technical grade high-content divinylbenzene. From among the synthesized adsorption resins,one resin was selected owing to its superior adsorption capacity for erythromycin,similar to the imported resin Amberlite XAD-16. The erythromycin extraction technology using macroporous resin was also studied, including the selection of resin and eluent,adsorption and elution conditions. Experiments showed that for a resin type P T4 the optimal conditions were as follows: pH9.2, flow rate 4BV/h, with a dynamic adsorption capacity for erythromycin achieving 12.2×10 4μ/g wet resin. When eluting with butyl acetate at a flow rate of 0.5BV/h and elution volume of 2.5BV/h, the desorption rate was 92%.