文献类型：期刊文献

英文题名：Highly selective asymmetry transfer hydrogenation of prochiral acetophenone catalyzed by palladium-chitosan on silica

作者：Sun, Yanxi[1]; Guo, Yun[1]; Lu, Quanzhong[1]; Meng, Xianle[1]; Xiaohua, Wu[1]; Guo, Yanglong[1]; Wang, Yunsong[1]; Liu, Xiaohui[1]; Zhang, Zhigang[1]

机构：[1]E China Univ Sci & Technol, Res Inst Ind Catalysis, Adv Mat Lab, Shanghai 200237, Peoples R China

年份：2005

卷号：100

期号：3-4

起止页码：213

外文期刊名：CATALYSIS LETTERS

收录：;EI(收录号：2005299227522);WOS:【SCI-EXPANDED(收录号:WOS:000228226800016)】；

语种：英文

外文关键词：palladium-chitosan; chiral catalyst; acetophenone; 1-phenyl ethanol; transfer hydrogenation; enantioselectivity

摘要：The chitosan - palladium catalyst supported on silica was prepared and used to catalyze an asymmetry transfer hydrogenation of prochiral acetophenone to alcohol with formate salts as a hydrogen donor at atmosphere. The results indicate that palladium coordinates with amino group in chitosan to form palladium - chitosan complex and its performance for an asymmetry transfer hydrogenation of acetophenone is affected greatly by the reaction temperature, hydrogen donor and solvent. For the hydrogenation of acetophenone over the palladium - chitosan - silica catalyst, the suitable solvent is ethanol and hydrogen donor is ammonium formate or sodium formate. Using ammonium formate as H-donor at atmosphere and 80 degrees C, an enantiomeric excess of R-1-phenylethanol reaches 68.9%.