文献类型：期刊文献

英文题名：Copper-Catalyzed Trifluoromethylthiolation of Aryl Halides with Diverse Directing Groups

作者：Xu, Jiabin[1];Mu, Xin[2];Chen, Pinhong[2];Ye, Jinxing[1];Liu, Guosheng[2]

机构：[1]E China Univ Sci & Technol, Sch Pharm, Minist Educ, Engn Res Ctr Pharmaceut Proc Chem, Shanghai 200237, Peoples R China;[2]Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China

年份：2014

卷号：16

期号：15

起止页码：3942

外文期刊名：ORGANIC LETTERS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000339982300024)，CCR-EXPANDED(收录号:WOS:000339982300024)】；

基金：We are grateful for financial support from the 973 program (No. 2011CB808700), NSFC (Nos. 21225210, 21202185, and 21121062), STCSM (11JC1415000), and CAS/SAFEA International Partnership Program for Creative Research Teams.

语种：英文

摘要：The expansion of cross-coupling components in Cu-catalyzed C-X bond forming reactions have received much attention recently. A novel Cu-catalyzed trifluoromethylthioladon of aryl bromides and iodides with the assistance of versatile directing groups such as pyridyl, methyl ester, amide, imine and oxime was reported. CuBr was used as the catalyst, and 1,10-phenanthroline as the ligand. By changing the solvent from acetonitrile to DMF, the coupling process could even take place at room temperature.