文献类型：期刊文献

英文题名：Three new diphenylpropanes from Celastrus hindsii

作者：Hu, Xian Qing[1];Han, Wei[1];Han, Zhu Zhen[2];Liu, Qing Xin[2];Xu, Xi Ke[2];Fu, Peng[2];Li, Hui Liang[2]

机构：[1]E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China;[2]Second Mil Med Univ, Sch Pharm, Shanghai 200433, Peoples R China

年份：2014

卷号：37

期号：11

起止页码：1411

外文期刊名：ARCHIVES OF PHARMACAL RESEARCH

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000345635900006)】；

基金：The work was supported by program NCET Foundation, NSFC (81230090, 81102335), partially supported by Global Research Network for Medicinal Plants (GRNMP) and King Saud University, Shanghai Leading Academic Discipline Project (B906), FP7-PEOPLE-IRSES-2008 (TCMCANCER Project 230232), Key laboratory of drug research for special environments, PLA, Shanghai Engineering Research Center for the Preparation of Bioactive Natural Products (10DZ2251300) and the Scientific Foundation of Shanghai China (12401900801, 09DZ1975700, 09DZ1971500, 10DZ1971700, 11QA1408200). National Major Project of China (2011ZX09307-002-03). National Key Technology R&D Program of China (2012BAI29B06).

语种：英文

外文关键词：Celastrus hindsii; Celastraceae; Diphenylpropanes; Arylpropyl quinone; Cytotoxicity

摘要：Three new diphenylpropanes, Hindsiipropane A-C (1-3), together with one known arylpropyl quinone Griffithane D (4), were isolated from Celastrus hindsii. Their structures were established by 1D and 2D nuclear magnetic resonance spectroscopic analysis, and mass spectroscopy. Compound 4 was firstly obtained in this genus. All the isolated compounds were evaluated in vitro for cytotoxicity against four human tumor cell lines (A549, HCT116, MDA-MB-231, BEL7404) by the MTT assay.