文献类型：期刊文献

英文题名：Tunable protic ionic liquids as solvent-catalysts for improved synthesis of multiply substituted 1,2,4-triazoles from oxadiazoles and organoamines

作者：Chen, Xiaofeng[1];Liu, Rui[1];Xu, Yuan[1];Zou, Gang[1]

机构：[1]E China Univ Sci & Technol, Dept Fine Chem, Shanghai 200237, Peoples R China

年份：2012

卷号：68

期号：24

起止页码：4813

外文期刊名：TETRAHEDRON

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000304798800030)，CCR-EXPANDED(收录号:WOS:000304798800030)】；

基金：Financial supports from the National Nature Science Foundation of China (No. 20972049) are gratefully acknowledged.

语种：英文

外文关键词：Protic ionic liquid; 1,2,4-Triazole; Oxadiazole; Tunable catalysis

摘要：More than green alternatives to traditional volatile molecular organic solvents, protic ionic liquids as dual solvent-catalysts have been successfully used to promote reactions of organoamines with oxadiazoles to afford sterically hindered 1,2,4-triazoles. Among the tested protic ionic liquids, pyridinium trifluoroacetate and acetate showed the highest efficiency for the reactions of arylamines and alkylamines, respectively, indicating that tunable catalysis could be readily effected with protic ionic liquid solvent-catalysts by simply tuning their cation and anion counterparts. A general and efficient approach has been developed for synthesis of multiply substituted 1,2,4-triazoles based on the tunable protic ionic liquid solvent-catalyst systems. (C) 2012 Elsevier Ltd. All rights reserved.