文献类型：期刊文献

英文题名：Aqueous heterogeneous synthesis of polysubstituted 2,6-dicyanoanilines via combined microwave and ultrasound-assisted multicomponent reaction

作者：Feng, Huangdi[1,2];Lin, Shengjie[1];Wang, Jiayi[1];Song, Gonghua[1];Peng, Yanqing[1]

机构：[1]E China Univ Sci & Technol, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China;[2]Chinese Acad Sci, Shanghai Inst Mat Med, Chinese Natl Compound Lib, Shanghai 201203, Peoples R China

年份：2012

卷号：1

期号：5

起止页码：463

外文期刊名：GREEN PROCESSING AND SYNTHESIS

收录：;EI(收录号：20224413047870);WOS:【SCI-EXPANDED(收录号:WOS:000208887300007)】；

基金：Financial support for this work from National Basic Research Program of China (973 Program) (grant 2010CB126101), National Key Technology R&D Program (grant no. 2011BAE06B05-4) are gratefully acknowledged.

语种：英文

外文关键词：2,6-dicyanoanilines; microwave; multicomponent reaction; ultrasound; water

摘要：A series of polysubstituted 3-aryl-2,6-dicyanoaniline derivatives were synthesized by one-pot multicomponent heterogeneous domino reaction of aromatic aldehyde, malononitrile and cyclic ketone under combined microwave and ultrasound irradiation in water. This facile approach reduces the reaction time and energy consumption and increases the yield and selectivity of the product.