文献类型：期刊文献

英文题名：Pt-Pd bimetallic nanocoral modified carbon fiber microelectrode as a sensitive hydrogen peroxide sensor for cellular detection

作者：Li, Hong[1];Zhao, Hongli[1];He, Haiyan[1];Shi, Libo[1];Cai, Xuan[1];Lan, Minbo[1,2]

机构：[1]East China Univ Sci & Technol, Shanghai Key Lab Funct Mat Chem, Sch Chem & Mol Engn, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China

年份：2018

卷号：260

起止页码：174

外文期刊名：SENSORS AND ACTUATORS B-CHEMICAL

收录：;EI(收录号：20180204616502);WOS:【SCI-EXPANDED(收录号:WOS:000424884300020)】；

基金：This research was financially supported by the Science and Technology Commission of Shanghai Municipality (No.16520710800), and the Fundamental Research Funds for the Central Universities (No.222201717022).

语种：英文

外文关键词：Carbon fiber microelectrode; Pt-Pd nanocoral; Electrode position; Hydrogen peroxide; Cellular detection

摘要：In this work, an ultrasensitive microelectrode for hydrogen peroxide (H2O2) detection was constructed. The carbon fiber microelectrode (CFME) was modified with Pt-Pd nanocoral (Pt-Pd/CFME) by using a one-step electrochemical deposition method. Compared to Pt/CFME and Pd/CFME, the Pt-Pd/CFME has larger active surface area and faster electron transfer efficiency, thus exhibiting higher electrocatalytic activity for H2O2 sensing. Under the optimal condition, the Pt-Pd/CFME presents fast response time (<= 5 s), high selectivity (11.6 mA mM(-1) cm(-2)), wide linear range (5-3920 mu M) and low detection limit (0.42 mu M, S/N = 3) for H2O2 detection. Furthermore, the proposed sensor was successfully employed to monitor H2O2 released from A549 living cells, and the detection of H2O2 in milk was also realized. With the above attractive electrocatalytic properties and convenient fabrication process, the as-prepared microelectrode provides unique advantages in the monitor of H2O2 in biological samples, especially in cellular environment. (c) 2017 Elsevier B.V. All rights reserved.