文献类型：期刊文献

英文题名：Fluorescent Probes for the Detection of Hydrogen Sulfide in Biological Systems

作者：Xuan, Weimin[2];Sheng, Chunquan[1];Cao, Yanting[2];He, Wenhan[2];Wang, Wei[2,3]

机构：[1]Second Mil Med Univ, Sch Pharm, Dept Med Chem, Shanghai 200433, Peoples R China;[2]Univ New Mexico, Dept Chem & Chem Biol, Albuquerque, NM 87131 USA;[3]E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China

年份：2012

卷号：51

期号：10

起止页码：2282

外文期刊名：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

收录：;EI(收录号：20121114852131);WOS:【SCI-EXPANDED(收录号:WOS:000300934700001)】；

基金：Financial support of the authors' research is provided by the National Science Foundation (CHE-1057569), the China 111 Project (Grant B07023), and the East China University of Science & Technology, and is gratefully acknowledged.

语种：英文

外文关键词：azides; fluorescein; fluorescent probes; hydrogen sulfide; rhodamines

摘要：Detective work: Three highly sensitive and selective fluorescent probes for the detection of H2S have been developed. Two of the probes detect H2S by the reduction of an azide moiety to an amine group, which changes the probes into their fluorescent forms and generates a fluorescent signal. In the third method, the fluorescent signal is created by using H 2S as a nucleophile in a reaction that unmasks fluorescein. Copyright ? 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.